G-protein signalling mediates differential production of toxic secondary metabolites
نویسندگان
چکیده
منابع مشابه
Production of Secondary Metabolites in Extreme Environments: Food- and Airborne Wallemia spp. Produce Toxic Metabolites at Hypersaline Conditions
The food- and airborne fungal genus Wallemia comprises seven xerophilic and halophilic species: W. sebi, W. mellicola, W. canadensis, W. tropicalis, W. muriae, W. hederae and W. ichthyophaga. All listed species are adapted to low water activity and can contaminate food preserved with high amounts of salt or sugar. In relation to food safety, the effect of high salt and sugar concentrations on t...
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Based on recent statistical survey, the cancer is the third important factor in Iran mortality. Vinblastine and vincristine alkaloids are dominantly biosynthesized in the aerial parts of periwinkle, broadly applied for cancer treatment. Therefore, over production of these alkaloids by using the biotechnological approaches is inevitable. Since the terpenoid indole alkaloids (TIAS) biosynthesis p...
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Microbial secondary metabolites are compounds produced mainly by actinomycetes and fungi, usually late in the growth cycle (idiophase). Although antibiotics are the best known secondary metabolites (SM), there are others with an enormous range of other biological activities mainly in fields like: pharmaceutical and cosmetics, food, agriculture and farming. These include compounds with anti-infl...
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Synchronous oscillations of thousands of cellular clocks in the suprachiasmatic nucleus (SCN), the circadian centre, are coordinated by precisely timed cell-cell communication, the principle of which is largely unknown. Here we show that the amount of RGS16 (regulator of G protein signalling 16), a protein known to inactivate Gαi, increases at a selective circadian time to allow time-dependent ...
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In biotechnology has been concentrated to review alternative routes for the production of natural compounds. Plant cell culture systems are viable alternatives for the production of secondary metabolites that are of commercial importance in food and pharmaceutical industries. However, relatively very few cultures synthesize these compounds over extended periods in amounts comparable to those fo...
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ژورنال
عنوان ژورنال: Molecular Microbiology
سال: 2000
ISSN: 0950-382X,1365-2958
DOI: 10.1046/j.1365-2958.2000.02166.x